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v-Myb proteins and their oncogenic potential: A study on how two point mutations affect the interaction of v-Myb with other proteins James J September 24-26

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September 24-26

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Volume 4 Enzymes in the Nervous System

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v-Myb proteins and their oncogenic potential: A study on how two point mutations affect the interaction of v-Myb with other proteins James J September 24-26The oncogene v myb of the retroviruses AMV (avian myeloblastosis virus) and E26 (avian leukaemia virus) encodes a transcription factor (v Myb) which is a truncated homolog of its cellular progenitor c Myb. c Myb plays an essential role in the development of haematopoietic cells and is known to be a regulator for many target genes. v Myb AMV is responsible for the transformation of myelomonocytic cells and for arresting them in an immature stage,

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